Dennis and Dee's Nazi grandfather is wasting away in a hospital, and it's their choice whether to pull the plug or not. Meanwhile, Charlie and Mac go crazy trying to find a dog painting they think has a lot of value.
While the city of Philadelphia's garbage men are on strike, Dennis, Mac, and Charlie decide to start a trash pick up business. And while being a big success, they must find out where to put this newly picked up trash.
When Dee gets asked by her therapist to bring in her so called 'issues,' Dee brings in the whole gang. And since they have all been called in, they have their own one on one therapy sessions, while many issues arise.
Under threat of a hostile takeover, the board of Frank's old company calls him back to run the company. As before, Frank maximizes the company's product: money. Dennis, Mac and Dee find Phillies VIP tickets and find themselves in a business deal of their own.
The gang starts playing an online video game and Charlie becomes obsessed with becoming the best player in the game. Meanwhile, Dennis is upset everyone else is playing the game all the time and not out enjoying the real world.